A new C31 dammarane-type triterpenoid saponin has been isolated from the roots of Ampelozizyphus amazonicus. Its structure was elucidated to be ampelozigenin-15α-O-acetyl-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside by 1D and 2D NMR spectroscopic methods, and by chemical transformations. Ampelozigenin is a novel triterpene, (20R,22R)-16β,22:16α,30-diepoxydammar-24(24')-methylene-3β,15α,20-triol.
NCBI PubMed ID: 7764239Publication DOI: 10.1016/s0031-9422(00)90728-3Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Laboratório de Farmacognosia, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil