Two new glycosides of ionone derivatives, icarisides B_3 (2) and B_4 (3), as well as a new phenylethanoid glycoside, icariside D_4 (4), and two new lignan glycosides, icarisides E_1 (12) and E_2 (13), have been isolated from Epimedium grandiflorum MORR. var. thunbergianum (MiQ.) NAKAI, together with eight known glycosides. The structures of the new compounds were established on the basis of chemical evidence and spectral data.
phenylethanoid glycoside, lignan glycoside, Epimedium grandiflorum var. thunbergianum, ionone derivative, icariside B, icariside D, icariside E
Publication DOI: 10.1248/cpb.35.3713Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Shizuoka College of Pharmacy, Japan, Central Research Laboratories, Yomeishu Seizo Co. Ltd., Japan
Methods: 13C NMR, 1H NMR, IR, acid hydrolysis, GC, UV, enzymatic digestion, CD, acetylation analysis