A new guaiane-type sesquiterpene glycoside, cynaroside A, seven new ursane-type saponins, cynarasaponins A-G, and three new oleanase-type saponins, cynarasaponins H-J, have been isolated from Cynara cardunculus L., together with a known guaiane-type sesquiterpene glycoside, 11β,13-dihydrodesacylcynaropicrin-8-β-D-glucoside, and a known oleanane-type saponin, chikusetsusaponin IVa. The structures of the new compounds were established on the basis of chemical and spectral data. This is the first isolation of saponin from Compositae plants.
sesquiterpene glycoside, compositae, saponin, Cynara cardunculus, cynarasaponin
Publication DOI: 10.1248/cpb.36.2466Journal NLM ID: 0377775WWW link: http://ci.nii.ac.jp/naid/110003627095Publisher: Pharmaceutical Society Of Japan
Institutions: School of Pharmaceutical Sciences, University of Shizuoka, Japan
Methods: 13C NMR, 1H NMR, partial acid hydrolysis, acid hydrolysis, MS, enzymatic digestion, reduction, acetylation analysis
Found