Ten new glycosides, icarisides A_2-A_4,B_5-B_7,E_3,F_1-F_2 and G_1,were isolated from the polar fraction of the water extract of Epimedium grandiflorum MORR. var. thunbergianum (MIQ.) NAKAI, together with three known glycosides, phenethyl glucoside, (Z)-3-hexenyl glucoside and blumenol C glucoside. Their structures were established on the basis of chemical evidence and spectral data.
9, Epimedium grandiflorum var. thunbergianum, ionone derivative, icariside B, icariside E, 10-dihydrophenanthrenol glycoside, bibenzyl glycoside, lignan, icariside A, icariside F, icariside G
Publication DOI: 10.1248/cpb.36.2475Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: School of Pharmaceutical Sciences, University of Shizuoka, Japan, Central Research Laboratories, Yomeishu Seizo Co., Ltd., Japan
Methods: 13C NMR, 1H NMR, FAB-MS, acid hydrolysis, GC, HPLC, enzymatic digestion, acetylation analysis