Five new saponins, ilexosides XLI-XLV, were isolated from fresh leaves of Ilex rotunda, and their structures were elucidated on the basis of chemical and physicochemical evidence. Ilexoside XLI is rotundic acid 28-O-α-D-glucopyranosyl(1→6)-β-D-glucopyranoside, ilexoside XLII is 23-oxorotungenic acid 28-O-β-D-glucopyranoside, ilexoside XLIII is 30-hydroxyrotundic acid 28-O-β-D-glucopyranoside, ilexoside XLIV is 3,28,bis-O-β-D-glucopyranosyl ilexosapogenin B (3-O-β-D-glucopyranosyl 23,30-dihydroxyursolic acid 28-O-β-D-glucopyranoside), and ilexoside XLV is 24-hydroxyrotundioic acid 28-O-β-D-glucopyranoside.
Aquifoliaceae, ilexoside, Ilex rotunda, α-glucoside, ilexosapogenin B, rotundic acid
Publication DOI: 10.1248/cpb.41.39Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan
Methods: 13C NMR, 1H NMR, EI-MS, FAB-MS, TLC, acid hydrolysis, HPLC, enzymatic digestion
Found