Six new saponins, ilexosides XLVI-LI, were isolated from fresh leaves of Ilex rotunda, and their structures were elucidated on the basis of chemical and physicochemical evidence. Ilexosides XLVI, XLVII, L and LI are 3,28-bisglycosides of ilexosapogenin A, spathodic acid, bredemolic acid, and siaresinokic acid, respectively. Ilexosides XLVIII and XLIX are 3,28-bisglycosides of hederagenin.
triterpenoid saponin, Aquifoliaceae, ilexoside, Ilex rotunda, ilexosapogenin A, bredemolic acid
Publication DOI: 10.1248/cpb.41.77Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan
Methods: 13C NMR, 1H NMR, EI-MS, FAB-MS, TLC, acid hydrolysis, methanolysis, HPLC, CC