Steroidal constituents from the roots of Apocynum cannabinum L. were investigated. (20S)-, (20R)-18,20-Epoxycymarin and (20S)-18,20-epoxyapocannoside were isolated along with cannogenin, strophanthidin and cannogenol glycosides, including D-cymaroside, D-oleandroside, D-digitoxoside and D-digitaloside, and their glucosyl, cellobiosyl or gentiobiosyl glycosides. Two pregnanes, neridienone A and 6,7-didehydrocortexone, were obtained, accompanied with cardenolides.
6, neridienone A, Apocynum cannabinum, 18, 20-epoxystrophanthidin, cannogenin trioside, cardenolide, 7-didehydrocortexone
Publication DOI: 10.1248/cpb.42.2028Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Fukuoka University, Japan
Methods: 13C NMR, 1H NMR, FAB-MS, TLC, HPLC
Found