Two new rearranged lanosterol trisaccharides, peruvianosides A (1) and B (2), were isolated from fresh bulbs of Scilla peruviana. Their structures were established mainly by extensive 2D NMR analysis. Peruvianoside A (1) showed an inhibitory activity on cyclic adenosine monophosphate (AMP) phosphodiesterase.
Publication DOI: 10.1246/bcsj.66.1182Journal NLM ID: 7505371Publisher: Tokyo: Nippon Kagakukai
Institutions: Tokyo College of Pharmacy, Tokyo, Japan, School of Pharmaceutical Sciences, Toho University, Japan
Methods: 1H NMR, NMR-2D, FAB-MS, acid hydrolysis, optical rotation measurement, acetylation, assay of cyclip AMP phosphodiesterase activity