Two new lupane-triterpene glycosides, acankoreoside A (1) and B (2), were isolated from the leaves of Acanthopanax koreanum NAKAI (Araliaceae). Based on spectroscopic data, the chemical structures of 1 and 2 were determined as 3 alpha-hydroxy-lup-20(29)-en-23,28-dioic acid 28-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester and 3 alpha,11 alpha,23-trihydroxy-lup-20(29)-en-28-oic acid 28-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester, respectively.
leaf, araliaceae, Acanthopanax koreanum, lupane-triterpene glycoside, acankoreoside A and B
Publication DOI: 10.1248/cpb.46.163Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Faculty of Pharmaceutical Sciences, Kumanoto University, Kumamoto, Japan, College of Pharmacy, Kyung-Hee University, Seul, Korea
Methods: 13C NMR, 1H NMR, EI-MS, IR, GLC, extraction, optical rotation measurement, melting point determination, HMBC, HR-FAB-MS, TLS, aid hydrolysis
Found