Eight new coumarin glycosides were isolated from the methanolic extract of the root and rhizoma of Glehnia littoralis FR. SCHMIDT ex MIQ. (Umbelliferae; "hamabofu" in Japanese). From the results of spectral investigation, they were characterized as glycosides of (S)-peucedanols, (S)-7-O-methylpeucedanols, marmesin and hydroxyimperatorin derivatives, respectively.
Umbelliferae, Glehnia littoralis, peucedanol glycoside, 7-O-peucedanol glycoside, hydroxyimperatorin glycoside
Publication DOI: 10.1248/cpb.46.1404Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Showa College of Pharmaceutical Sciences, Higashi Tamagawa Gakuen, Japan
Methods: 13C NMR, 1H NMR, FAB-MS, enzymatic hydrolysis, acid hydrolysis, HPLC, extraction, optical rotation measurement, CC, COSY