Four novel 3 α-hydroxy-oleanane type triterpene oligoglycosyl esters, spinoside C2, C3, C6 and C7, were isolated from the leaves of Acanthopanax spinosus. The structures were established to be 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl esters of 3α,30-dihydroxy-23-oxo-olean-12-en-28-oic acid, 3α,20α-dihydroxy-30-nor-olean-12-en-28-oic acid, 3α,20α-dihydroxy-23-oxo-30-nor-olean-12-en-28-oic acid and 3α,20α, 23-trihydroxy-30-nor-olean-12-en-28-oic acid.
araliaceae, triterpenoid saponin, Acanthopanax spinosus, 3α, triterpene glycosyl ester, 20α-dihydroxy-30-nor-olean-12-en-28-oic acid, 20α-dihydroxy-23-oxo-30-nor-olean-12-en-28-oic acid, 20α, 23-trihydroxy-30-nor-olean-12-en-28-oic acid, 3a, 30-dihydroxy-23-oxo-olean-12-en-28-oic acid, spinogenin, spinoside
Publication DOI: 10.1016/S0031-9422(97)80022-2Journal NLM ID: 0151434Publisher: Elsevier
Institutions: School of Pharmaceutical Sciences, Showa University, Hatanodai 1-5-8, Shinagawa-ku, Tokyo 142, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, TLC, acid hydrolysis, GC, HPLC, extraction, reduction