A new bisdesmosidic cholestane glycoside, designated as concinnasteoside A, was isolated from the fresh stems of Dracaena concinna. The structure was determined to be 1β,3β,16β-trihydroxy-5 α-cholesta-7,23-dione 1-O-α-L-rhamnopyranosyl 16-O-β-D-glucopyranoside on the basis of spectroscopic analysis, including 2D NMR techniques. Concinnasteoside A is believed to be the first example of a cholestane glycoside from a plant of the genus Dracaena.
Publication DOI: 10.1021/np9703095Journal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: mimakiy@ps.toyaku.ac.jp
Institutions: School of Pharmacy, Tokyo University of Pharmacy and Life Science, Horinouchi 1432-1, Hachioji, Tokyo 192-03, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, TLC, conformation analysis, acid hydrolysis, NMR-1D, HPLC