A rearranged cadinane sesquiterpene glycoside named tinocordiside (1), consisting of a tricyclic skeleton with a cyclobutane ring, has been isolated from the immunomodulatory aqueous fraction of the Indian medicinal plant Tinospora cordifolia. The structure has been established by spectroscopic and chemical methods.
Publication DOI: 10.1021/np970169zJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: ram@nii.ernet.in
Institutions: Bio-organic Chemistry Lab, National Institute of Immunology, Aruna Asaf Ali Marg, JNU Complex, New Delhi 110067, India
Methods: 13C NMR, 1H NMR, NMR-2D, IR, TLC, ESI-MS, acid hydrolysis, chemical methods, HPLC, extraction