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Structure type: oligomer ; 707 [M+Na]+
Trivial name: 7S,8R,8’R-(-)-lariciresinol-4,4’-bis-O-β-D-glucopyranoside
Compound class: lignan glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 11132
  ElGamal AA, Takeya K, Itokawa H, Halim AF, Amer MM, Saad HEA "Lignan bis-glucosides from Galium sinaicum" - Phytochemistry 45(3) (1997) 597-600
  

  The new lariciresinol-based lignan bis-glucosides, 7S,8R,8′R-(−)-lariciresinol-4,4′-bis-O-β-d-glucopyranoside and 7S,8R,8′R-(−)-5-methoxylariciresinol-4,4′-bis-O-β-d-glucopyranoside, together with (−)-syringaresinol-4,4′-bis-O-β-d-glucopyranoside were isolated from the n-butanol extract of Galium sinaicum roots and their structures were established by various spectroscopic techniques. The isolated compounds represent the first report of lignan glycosides from the Rubiaceae. The two lariciresinol-type glucosides exhibited weak cytotoxic activity against the P388 cell line.

  cytotoxic activity, roots, Rubiaceae, Galium sinaicum, lignan glycosides

  Publication DOI: 10.1016/S0031-9422(96)00881-3
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Institutions: University of Mansoura, Faculty of Pharmacy, El-Mansoura-35516, Egypt
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, enzymatic hydrolysis, chemical methods
  
   
  
  Galium sinaicum
  CSDB ID 60263 (all data & tools)