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Structure type: monomer ; 441.1389 [M+H]+
C₂₀H₂₄O₁₁
Trivial name: tetrahydroswertianolin
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 11166
  Hase K, Kadota S, Basnet P, Li JX, Takamura S, Namba T "Tetrahydroswertianolin: A potent hepatoprotective agent from Swertia japonica Makino" - Chemical and Pharmaceutical Bulletin 45(3) (1997) 567-569
  

  Tetrahydroswertianolin (1), a new tetrahydroxanthone glycoside, was isolated from the whole plant of Swertia japonica Makino (Gentianaceae). Its structure was determined by chemical and spectroscopic methods including 2D-NMR. This compound was found to be very effective in immunologically induced liver injury in mice.

  Gentianaceae, Swertia japonica, tetrahydroswertianolin, tetrahydroxanthone, D-galactosamine/lipopolysaccharide-induced liver injury

  Publication DOI: 10.1248/cpb.45.567
  Journal NLM ID: 0377775
  Publisher: Pharmaceutical Society Of Japan
  Institutions: Research Institute for Wakan-Yaku (Traditional Sino-Japanese Medicines), Toyama Medical and Pharmaceutical University, 2630-Sugitani, Toyama 930-01, Japan
  Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, chemical methods, biological assays, extraction
  
   
  
  Swertia japonica Makino
  CSDB ID 60501 (all data & tools)