Two new cycloartane-type triterpenoidal saponins, huangqiyenins A and B, were isolated from the leaves of Astragalus membranaceus BUNGE (Leguminosae) collected in Heilongjiang Province, China, and established as 3-O-β-D-glucopyranosyl-(20R,24S)-16β,25-dihydroxy-20,24-epoxy-9,19-cyclolanost-6-one and 3-O-β-D-glucopyranosyl-(24S)-16β,24,25-trihydroxy-cyclolanost-6-one, respectively, on the basis of chemical and spectral evidence.
triterpenoidal saponin, Astragalus membranaceus, cycloartane, huangqiyenin A, huangqiyenin B
Publication DOI: 10.1248/cpb.45.359Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Heilongjiang University of Traditional Chinese Medicine
Methods: 13C NMR, 1H NMR, IR, enzymatic hydrolysis, ESI-MS, chemical methods, extraction, CC, HR-FAB-MS