A flavonoid glycoside was isolated from Anthocepharus chinensis. Its structure was elucidated by spectral data and determined to be myricetin 3-O-(4"-acetyl)-alpha-fucoside. This flavonoid glycoside and its aglycone showed potent inhibition against rat and porcine lens aldose reductase. The flavonoid aglycone also inhibited sorbitol accumulation in human red blood cells.
Enzymes, derivatives, flavonoids
NCBI PubMed ID: 9491768Publication DOI: 10.1055/s-2006-957369Journal NLM ID: 0066751Publisher: George Thieme
Institutions: Faculty of Engineering, Fukuyama University, Fukuyama, Japan, Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, Fukuyama, Japan
Methods: 13C NMR, 1H NMR, TLC, extraction, optical rotation measurement, CC
Found