Four triterpenoid saponins were isolated from Berneuxia thibetica. On the basis of chemical and spectroscopic evidence, three new saponins, berneuxia saponins A, B and C, were elucidated as 21-tigloylbarringtogenol C- 3β-O-α-L-rhamnopyranosyl(1 → 2)-β-D-galactopyranosyl(l → 3)[β-D- glucopyranosyl (1 → 2)-β-D-glucuronopyranoside], 28-tigloylbarringtogenol C-3β-O-α-L-rhamnopyranosyl(1 → 2)-β-D-galactopyranosyl(1 → 3)[β-D- glucopyranosyl(1 → 2)-β-D-glucuronopyranoside] and 16α-28-dihydroxyolean- 12-en-21-one-3-O-α-L-rhamnopyranosyl(1 → 2)-β-D-galactopyranosyl(1 → 3)[β-D-glucopyranosyl(1 → 2)-β-D-glucuronopyranoside]. The known saponin was desacyl jegosaponin.
C, triterpenoid saponins, B, berneuxia saponins A, Berneuxia thibetica, desacyl jegosaponin, diapensiaceae
NCBI PubMed ID: 9720318Publication DOI: 10.1016/S0031-9422(97)00850-9Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Department of Chemistry, Zhejiang University, Hangzhou, China, Laboratory of Natural Materia Medica, Chengdu Institute of Biology, Chengdu, China
Methods: 13C NMR, 1H NMR, EI-MS, FAB-MS, acid hydrolysis, extraction, optical rotation measurement, CC
Found