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Structure type: oligomer ; 946
C₄₆H₇₄O₂₀
Trivial name: lasianthoside A
Compound class: triterpenoid glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_142489,IEDB_144144,IEDB_146664,IEDB_149135,IEDB_225177,IEDB_885823,IEDB_983931,SB_192,SB_86

• Article ID: 11570
  Qiu S, Cordell G, Kumar B, Rao Y, Ramesh M, Kokate C, Rao A "Bisdesmosidic pregnane glycosides from Caralluma lasiantha" - Phytochemistry 50(3) (1998) 485-491
  

  From the whole plant of Caralluma lasiantha, two new bisdesmosidic C-21 steroidal (pregnane) glycosides, named as lasianthoside-A and -B, were isolated and their structures elucidated solely based on extensive 2D-NMR and MS/MS spectral analysis as caralasigenin 3-O-β-D-glucopyranosyl(1 → 4)-β- D-digitalopyranoside-20-O-α-L-rhamnosyl(1 → 6)-β-D-glucopyranoside and caralumagenin 3-O-β-D-glucopyranosyl(1 → 4)-β-D-digitalopyranoside-20-O- α-L-rhamnosyl(1 → 6)-β-D-glucopyranoside. In addition, a known flavonoid glycoside, luteolin neohesperidoside, was also isolated.

  structure elucidation, Asclepiadaceae, NMR assignments, two-dimensional NMR techniques, Caralumagenin, bisdesmosidic pregnane steroidal glycosides, caralasigenin, Caralluma lasiantha, lasianthoside-A, lasianthoside-B, luteolin neohesperidoside

  Publication DOI: 10.1016/S0031-9422(98)00569-X
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Correspondence: Cordell G
  Institutions: Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, Chicago, US, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India, Dr. Reddy's Research Foundation, Miyapur, Hyderabad, India
  Methods: 1H NMR, IR, FAB-MS, ESI-MS, extraction, optical rotation measurement, ROESY, TOCSY, DCI-MS, melting point determination, HMBC, HMQC, DEPT, HOHAHA, liquid chromatography
  
   
  
  Caralluma lasiantha
  CSDB ID 63436 (all data & tools)

Show legend Show as text

Structure type: oligomer ; 969 [M+Na]+
C₄₆H₇₄O₂₀
Trivial name: lasianthoside A
Compound class: saponin glycoside
Contained glycoepitopes: IEDB_136105,IEDB_142488,IEDB_142489,IEDB_144144,IEDB_146664,IEDB_149135,IEDB_225177,IEDB_885823,IEDB_983931,SB_192,SB_86

• Article ID: 11946
  Qiu SX, Cordell GA, Kumar BR, Rao YN, Ramesh M, Kokate C, Venkata A, Rao NA "Studies on the C-21 steroids from Asclepiadaceous plants part VII - bisdesmosidic pregnane glycosides from Caralluma lasiantha" - Phytochemistry 50(3) (1999) 485-491
  

  From the whole plant of Caralluma lasiantha, two new bisdesmosidic C-21 steroidal (pregnane) glycosides, named as lasianthoside A and B, were isolated and their structures elucidated solely based on extensive 2D-NMR and MS/MS spectral analysis as caralasigenin 3-O-β-D-glucopyranosyl(1→4)-β-D-digitalopyranoside-20-O-α-L-rhamnosyl(1→6)-β-D-glucopyranoside and caralumagenin 3-O-β-D-glucopyranosyl(1→4)-β-D-digitalopyranoside-20-O-α-L-rhamnosyl(1→6)-β-D-glucopyranoside. In addition, a known flavonoid glycoside, luteolin neohesperidoside, was also isolated.

  structure elucidation, Asclepiadaceae, NMR assignments, two-dimensional NMR techniques, Caralumagenin, bisdesmosidic pregnane steroidal glycosides, caralasigenin, Caralluma lasiantha, luteolin neohesperidoside, lasianthoside A, lasianthoside B

  Publication DOI: 10.1016/S0031-9422(98)00569-X
  Journal NLM ID: 0151434
  Publisher: Elsevier
  Correspondence: Cordell GA
  Institutions: Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612 USA, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009 Andhra Pradesh, India, Dr. Reddy's Research Foundation, Bollaram Road, Miyapur, Hyderabad, India
  Methods: 13C NMR, 1H NMR, IR, FAB-MS, optical rotation measurement, ROESY, TOCSY, DCI-MS, DQF-COSY, HMBC, HMQC, DEPT, HOHAHA
  
   
  
  Caralluma lasiantha
  CSDB ID 64103 (all data & tools)