AIM: To find the chemical constituents of Prunella vulgaris L. METHODS: To separate the constituents of Prunella vulgaris by using various kinds of chromatography and identify their structures on the basis of spectral analysis. RESULTS: Six compounds were isolated from the spikes of Prunella vulgaris L. Their structures were established as 3β,16α,24-trihydroxyoleana-12-en-28-oic acid-3-O-(6′-butyryl)-β-D-glucopyranosid (I), ursolic acid (II), 2α,3α-dihydroxyurs-12-en-28-oic acid (III), quercetin (IV), quercetin-3-O-β-D-galactoside (V) and ethyl caffeate (VI) based on the analysis of spectral data of IR, UV FAB-MS, 1D and 2D-NMR. CONCLUSION: I was a new compound, named vulgarsaponin B, III was isolated for the first time from this plant, V and VI for the first time from the Prunella genus.
triterpenoid saponin, Labiate, Prunella vulgaris, vulgarsaponin B
Journal NLM ID: 21710340RWWW link: http://www.yxxb.com.cn:8081/aps/CN/abstract/abstract9158.shtmlPublisher: Beijing: Zhongguo yao xue hui
Correspondence: Chen Y
Institutions: Division of Natural Medicinal Chemistry, Beijing Medical University, Beijing, 100083, China, Beijing Institute of Microchemistry, Beijing 100083, China
Methods: 13C NMR, 1H NMR, IR, FAB-MS, UV, DEPT, HR-SI-MS
Found