Three new phenolic glycosides named eriosemasides A-C, one novel (named eriosematin F) and four known phenolic constituents were isolated from the n- BuOH-soluble fraction of the roots of Eriosema tuberosum. Their structures were established by spectroscopic analyses and chemical methods. All the phenolic compounds were fungitoxic except the phenolic glycosides.
phenolics, Leguminosae, Eriosema tuberosum, chromone glycoside, fungitoxic activity
Publication DOI: 10.1016/S0031-9422(99)00180-6Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Department of Applied Bioscience, Faculty of Agriculture, Hokkaido University, Kita-ku, Sapporo, 060-8589, Japan, CREST, Japan Science and Technology Corporation, 4-1-8 Honmachi, Kawaguchi 332-0012, Saitama, Japan, Debio Recherche Pharmaceutique SA, Case postale 368 Route du Levant 146, CH-1920, Martigny, Switzerland, Institut de Pharmacognosie et Phytochimie, Universite de Lausanne, BEP, CH-1015, Lausanne, Switzerland
Methods: 13C NMR, 1H NMR, IR, FAB-MS, TLC, enzymatic hydrolysis, UV, optical rotation measurement, HPTLC, FD-MS, HMBC, antifungal activity test, HCl hydrolysis, sulfuric acid hydrolysis