Panax vietnamensis Ha et Grushv., Araliaceae, is a new Panax species discovered in Central Vietnam in 1973. The plant, which is now commonly known as Vietnamese ginseng, has become an important medicinal plant of Vietnam. From the underground part of P. vietnamensis growing wild, twenty-four known saponins and fourteen new dammarane saponins named vina-ginsenosides R1-R14 were previously isolated and identified. In our course of further study on the saponin composition of P. vietnamensis, ten more new dammarane saponins, vina-ginsenosides R15-R24, were isolated along with two known saponins, pseudo-ginsenoside RC1 and gypenoside IX. The structure of the new saponins was elucidated based on chemical and spectroscopic evidence.
Vietnamese Ginseng, Panax vietnamensis, dammarane saponins, vinaginsenosides R15-R24
Publication DOI: 10.1016/S0928-3420(99)80010-XJournal NLM ID: 101589254Publisher: Toronto, ON: Canadian Center of Science and Education
Institutions: Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima 734, Japan, Department of Pharmacognosy, HCMC University of Medicine and Pharmacy, 41 Dinh Tien Hoang Street, District 1, HoChiMinh City, Vietnam, Suzugamine Women's College, Inokuchi 4-chome 6-18, Nishi-ku, Hiroshima 733, Japan