Flowers of Arnica longifolia were investigated for the occurrence of sesquiterpene lactone glycosides. A mixture containing the two isomeric 11α,13-dihydro- and 11β,13-dihydro-4H-tomentosin glucosides, previously isolated from A. amplexicaulis and A. mollis, together with the two isomeric 11α,13-dihydro- and 11β,13-dihydro-4H-carabrone glucosides were found in A. longifolia. All carbon and proton shifts of the glycosides could be assigned by their 2D-COSY and 2D-HETCOR spectra and spectroscopy of their respective aglycones, obtained via enzymatic hydrolysis.
Asteraceae, sesquiterpene lactones, sesquiterpene lactone glycosides, Arnica longifolia, xanthanolides, xanthanolide glucosides, carabrone glucosides
NCBI PubMed ID: 17260246Publication DOI: 10.1055/s-1999-13978Journal NLM ID: 0066751Publisher: George Thieme
Correspondence: Passreiter CM
Institutions: Institut für Pharmazeutische Biologie, Heinrich-Heine-Universität, Düsseldorf, Germany, Institut für Organische und Makromolekulare Chemie, Heinrich-Heine-Universität, Düsseldorf, Germany
Methods: 13C NMR, 1H NMR, EI-MS, TLC, enzymatic hydrolysis, GC, DCI-MS, COSY, HCl hydrolysis, HETCOR
Found