A new flavonol glycoside identified as myricetin 3-O-β-D-sorboside (1) has been isolated from the leaves of L. axillare. The new compound showed a moderate inhibition of Ehrlich ascites carcinoma cells.
antitumor activity, flavonoids, flavonol glycoside, Limonium axillare
NCBI PubMed ID: 11008378Publication DOI: 10.1002/1521-4184(20008)333:8<275::aid-ardp275>3.0.co;2-4Journal NLM ID: 0330167Publisher: Deutschen Apotheker-Vereins
Institutions: Natural and Microbial Products Department, National Research Centre, Cairo, Egypt, Chemistry of Tanning Materials and Proteins Department, National Research Centre, Cairo, Egypt, Pharmaceutical Department, National Research Centre, Cairo, Egypt, Medicinal Chemistry Department, National Research Centre, Cairo, Egypt
Methods: 13C NMR, 1H NMR, acid hydrolysis, biological assays, paper chromatography, UV, extraction, column chromatography, cytotoxicity assay, PPC