A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.
structure-activity relationships, digitalis glycosides analogues, inotropic activity, Na+, K+-ATPase, aminoguanidine analogues
Publication DOI: 10.3390/50100051Journal NLM ID: 100964009Publisher: Basel, Switzerland: MDPI
Correspondence: medarde@gugu.usal.es
Institutions: Departamento de QuĂmica FarmacĂ©utica, Facultad de Farmacia, Salamanca, Spain
Found