In continuation of our phytochemical studies on Caryopteris x clandonensis (Lamiaceae), three further iridoids were isolated from the methanolic extract of the stems. Their structures were established by 1D and 2D NMR and MS analysis as a C-6 epimer of 8-O-acetylharpagide (6-epi-8-O-acetylharpagide), a derivative of harpagide which contained the unusual feature of a 3',4' seco-glycopyranosyl moiety (clandonoside II) and a methyl cetal of 8-O-acetylharpagide aglucone hydrate named clandonensine.
Lamiaceae, Verbenaceae, Iridoids, 8-O-acetylharpagide, Caryopteris x clandonensis, seco-glycoside, 6-epi-8-O-acetylharpagide, clandonoside II, clandonensine
NCBI PubMed ID: 11014270Publication DOI: 10.1016/s0031-9422(00)00069-8Journal NLM ID: 0151434Publisher: Elsevier
Correspondence: shannedouche@hotmail.com
Institutions: Laboratoire Pharmacophores Redox, Phytochimie et Radiobiologie, Faculté des Sciences Pharmaceutiques, Toulouse, France
Methods: 13C NMR, 1H NMR, NMR-2D, ESI-MS, UV, extraction, optical rotation measurement, DCI-MS, CC
Found