From the methanolic extract of the roots of Sonchus asper, two new sesquiterpene glucosides, together with two known sesquiterpene glucosides and a known aglycone were isolated. Structures were identified as 11β,13-dihydrourospermal A, 15-O-β-D-glucopyranosyl-11β,13-dihydrourospermal A, 15-O-β-D-glucopyranosylurospermal A, 15-O-[6′-(p-hydroxyphenylacetyl)]-β-D-glucopyranosylurospermal A and 14-O-methylacetal-15-O-[6′-(p-hydroxyphenylacetyl)]-β-D-glucopyranosylurospermal A, by spectroscopic means.
Asteraceae, Sonchus asper, melampolides, sesquiterpene glucosides, urospermal A derivatives
NCBI PubMed ID: 10731026Publication DOI: 10.1016/s0031-9422(99)00516-6Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt, Department of Cell-Resources Engineering, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
Methods: 13C NMR, 1H NMR, EI-MS, FAB-MS, TLC, extraction, CC, evaporation, MPLC
Found