Four new triterpenoid saponins, ardisimamilloside C (1), 3-O-{α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}-3β, 16α, 28, 30-tetrahydroxy-olean 12-en, ardisimamilloside D (2), 3-Or-{α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}-3β, 15α, 28, 30-tetrahydroxy-olean-12-en, ardisimamilloside E (3), 3-O-{α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}-13β, 28-epoxy-3β, 16α, 29-oleananetriol, and ardisimamilloside F (4), 3-O-{α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}-3β, 16α-dihydroxy-13β, 28-epoxy-oleanan-30-oic acid were isolated from the roots of Ardisia mamillata HANCE. Structure assignments were established on the basis of highresolution (HR)-FAB-MS, 1H-, 13C-, and two-dimensional (2D)-NMR spectra, and on the chemical evidence.
D, triterpenoid saponin, E, F, Myrsinaceae, Ardisia mamillata, ardisimamilloside C
NCBI PubMed ID: 11045441Publication DOI: 10.1248/cpb.48.1413Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Correspondence: takeda-td@kyoritsu-ph.ac.jp
Institutions: Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan, Kyoritsu College of Pharmacy, Tokyo, Japan, School of Pharmaceutical Sciences, West China University of Medical Sciences, Chengdu, China
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, acid hydrolysis, GC, MALDI-TOF MS, HPLC, extraction, optical rotation measurement, acetylation, reduction, CC, precipitation, derivatization, evaporation, HR-FAB-MS
Found