Five germacrane- and guaiane-type sesquiterpene lactones, including two previously described taraxinic acid derivatives, were isolated from the roots of Taraxacum officinale, together with benzyl glucoside, dihydroconiferin, syringin and dihydrosyringin. The other three lactones were identified as 11β, 13-dihydrolactucin, ixerin D and ainslioside. Moreover, the stereochemistry at C-11 in dihydrotaraxinic acid was assigned.
phenylpropanoids, sesquiterpene lactones, germacranolides, guaianolides, Taraxacum officinale
NCBI PubMed ID: 10844166Publication DOI: 10.1016/s0367-326x(99)00158-6Journal NLM ID: 16930290RPublisher: Elsevier
Correspondence: Kisiel W
; Kisiel W
Institutions: Department of Phytochemistry, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
Methods: 1H NMR, HPLC, extraction, CC, PTLC