A novel bianthraquinone glycoside, 8-O-β-D-glucopyranosyl-1,1‘,8‘-trihydroxy-3,3‘-dimethyl-2,7‘-bianthraquinone (1); two naphthalene derivatives, 2-acetyl-1-hydroxy-8-methoxy-3-methylnaphthalene (2) and 2-acetyl-1,8-dimethoxy-3-methylnaphthalene (3); and a novel pre-anthraquinone,1-oxo-4(S),9-dihydroxy-8-methoxy-6-hydroxymethyl-1,2,3,4-tetrahydroanthracene (4), were isolated from Eremurus chinensis. Their structures were established by spectroscopic and chemical methods. In addition, the known compounds chrysophanol, chrysophanol 8-methyl ether, aloesaponol III 8-methyl ether (5), and 10-(chrysophanol-7‘-yl)-10-hydroxychrysophanol-9-anthrone were also isolated and identified from this plant.
identification, isolation, Eremurus chinensis, bianthraquinone glycoside
NCBI PubMed ID: 10843579Publication DOI: 10.1021/np9904915Journal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Shi JG
Institutions: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, Department of Pharmacy, Lanzhou Medical College, Lanzhou, China