From the leaves of Phlomis aurea, two new iridoids of unique structures named 3-epiphlomurin (1) and phlomurin (2), a new megastigmane glucoside phlomuroside (3) and a new benzyl alcohol glycoside having the structure benzyl alcohol-O-β-xylopyranosyl-(1→2)-β-glucopyranoside (4) have been isolated together with four known iridoids auroside, lamiide, 8-epiloganin and ipolamiide, two known phenolic glycosides acteoside (verbascoside) and syringin, one known phenylethanoid glycoside 2-phenylethyl-O-β-xylopyranosyl-(1→2)-β-glucopyranoside, one known lignan liriodendrin and three known flavonoids chrysoeriol-7-O-β-glucopyranoside, acacetin-7-O-β-glucopyranoside and luteolin-7-O-β-glucopyranoside. The structures of the isolated compounds were verified by means of mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectral analyses.
Lamiaceae, Iridoids, Phlomis aurea, megastigmane, benzyl alcohol glycosides
NCBI PubMed ID: 11117884Publication DOI: 10.1016/s0031-9422(00)00331-9Journal NLM ID: 0151434Publisher: Elsevier
Correspondence: mkamel@mailcity.com
Institutions: Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, Hiroshima, Japan, Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, HPLC, extraction, optical rotation measurement, CC, MPLC, HR-FAB-MS
Found