Show legend Show as text

Structure type: oligomer
Trivial name: schidigera-saponin F1
Compound class: glycoside
Contained glycoepitopes: IEDB_114701,IEDB_136044,IEDB_137472,IEDB_141794,IEDB_142488,IEDB_146664,IEDB_153218,IEDB_167188,IEDB_174332,IEDB_190606,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88

• Article ID: 12494
  Miyakoshi M, Tamura Y, Masuda H, Mizutani K, Tanaka O, Ikeda T, Ohtani K, Kasai R, Yamasaki K "Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent" - Journal of Natural Products 63(3) (2000) 332-338
  

  A saponin fraction from the stems of Yucca schidigera (Mohave yucca) exhibited potent growth-inhibitory activities against certain food-deteriorating yeasts, film-forming yeasts, and dermatophytic yeasts and fungi. From this fraction, a number of new anti-yeast monodesmosidic spirostanol saponins, named schidigera-saponins A1 (1), A2 (2), A3 (3), B1 (4), C1 (5),C2 (6); 25(R and S) schidigera-saponins D1 (7), D2 (8), E1 (12), F1 (13); and 25(S) schidigera-saponins D3 (9), D4 (10), D5 (11), and F2 (14) were isolated, together with several related known saponins, and the structures were elucidated by spectroscopic methods (see Chart 1). The relationship between the antiyeast activities and the structures of these saponins is described.

  steroidal saponins, schidigerasaponins, antiyeast activity, Yucca schidigera

  NCBI PubMed ID: 10757713
  Publication DOI: 10.1021/np9904354
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: miyakov@iea.att.ne.jp
  Institutions: Maruzen Pharmaceuticals Co., Ltd., Onomichi-city, Japan, Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, Hiroshima, Japan
  Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, HPLC, extraction, evaporation
  
   
  
  Yucca schidigera
  CSDB ID 66924 (all data & tools)

Show legend Show as text

Structure type: oligomer
Trivial name: schidigera-saponin F2
Compound class: glycoside
Contained glycoepitopes: IEDB_136044,IEDB_137472,IEDB_141794,IEDB_142488,IEDB_146664,IEDB_153218,IEDB_190606,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88

• Article ID: 12494
  Miyakoshi M, Tamura Y, Masuda H, Mizutani K, Tanaka O, Ikeda T, Ohtani K, Kasai R, Yamasaki K "Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent" - Journal of Natural Products 63(3) (2000) 332-338
  

  A saponin fraction from the stems of Yucca schidigera (Mohave yucca) exhibited potent growth-inhibitory activities against certain food-deteriorating yeasts, film-forming yeasts, and dermatophytic yeasts and fungi. From this fraction, a number of new anti-yeast monodesmosidic spirostanol saponins, named schidigera-saponins A1 (1), A2 (2), A3 (3), B1 (4), C1 (5),C2 (6); 25(R and S) schidigera-saponins D1 (7), D2 (8), E1 (12), F1 (13); and 25(S) schidigera-saponins D3 (9), D4 (10), D5 (11), and F2 (14) were isolated, together with several related known saponins, and the structures were elucidated by spectroscopic methods (see Chart 1). The relationship between the antiyeast activities and the structures of these saponins is described.

  steroidal saponins, schidigerasaponins, antiyeast activity, Yucca schidigera

  NCBI PubMed ID: 10757713
  Publication DOI: 10.1021/np9904354
  Journal NLM ID: 7906882
  Publisher: American Society of Pharmacognosy
  Correspondence: miyakov@iea.att.ne.jp
  Institutions: Maruzen Pharmaceuticals Co., Ltd., Onomichi-city, Japan, Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, Hiroshima, Japan
  Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, HPLC, extraction, evaporation
  
   
  
  Yucca schidigera
  CSDB ID 66925 (all data & tools)