Show legend Show as text

Structure type: monomer
Compound class: glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 12517
  Nagatsu A, Zhang H, Mizukami H, Okuyama H, Sakakibara J, Tokuda H, Nishino H "Tyrosinase inhibitory and anti-tumor promoting activities of compounds isolated from safflower (Carthamus Tinctorius L.) and cotton (Gossypium Hirsutum L.) oil cakes" - Natural Product Letters 14(3) (2000) 153-158
  

  Tyrosinase inhibitory and anti-tumor promoting activities of 14 compounds isolated from safflower and cotton oil cakes were evaluated together with the two genins of glycosides, trachorogenin (8a) and quercetin (12a). Catechin (11) and quercetin (12a) showed moderate tyrosinase inhibitory activity. N-(p-Coumaroyl)serotonin (1) and its 5-O-glucoside (3) exhibited weak anti-tyrosinase activity, but potent inhibitory activity on melanine production in the assay. Serotonin derivatives (1-4). 2-hydroxyarctiin (8), matairesinol glycoside (9) and sesquiterpene glucosides (13, 14) exhibited potent inhibitory activity on phorbol-12-myristate-13-acetate induced Epstein-Barr virus early antigen activation, which is the short term in vitro assay for anti-tumor-promoting activity.

  Antioxidant, tyrosinase inhibitor, safflower oil cake, cotton oil cake, anti-tumor-promoter

  Publication DOI: 10.1080/10575630008041225
  Journal NLM ID: 9315615
  Publisher: Taylor & Francis Health Sciences
  Institutions: Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan, Faculty of Pharmacy, Meijo University, Nagoya, Japan, Department of Biochemistry, Kyoto Prefectural University of Medicine, Kyoto, Japan
  Methods: biological assays
  
   
  
  Carthamus tinctorius, Gossypium hirsutum
  CSDB ID 67033 (all data & tools)

Show legend Show as text

Structure type: monomer
Compound class: glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192

• Article ID: 12517
  Nagatsu A, Zhang H, Mizukami H, Okuyama H, Sakakibara J, Tokuda H, Nishino H "Tyrosinase inhibitory and anti-tumor promoting activities of compounds isolated from safflower (Carthamus Tinctorius L.) and cotton (Gossypium Hirsutum L.) oil cakes" - Natural Product Letters 14(3) (2000) 153-158
  

  Tyrosinase inhibitory and anti-tumor promoting activities of 14 compounds isolated from safflower and cotton oil cakes were evaluated together with the two genins of glycosides, trachorogenin (8a) and quercetin (12a). Catechin (11) and quercetin (12a) showed moderate tyrosinase inhibitory activity. N-(p-Coumaroyl)serotonin (1) and its 5-O-glucoside (3) exhibited weak anti-tyrosinase activity, but potent inhibitory activity on melanine production in the assay. Serotonin derivatives (1-4). 2-hydroxyarctiin (8), matairesinol glycoside (9) and sesquiterpene glucosides (13, 14) exhibited potent inhibitory activity on phorbol-12-myristate-13-acetate induced Epstein-Barr virus early antigen activation, which is the short term in vitro assay for anti-tumor-promoting activity.

  Antioxidant, tyrosinase inhibitor, safflower oil cake, cotton oil cake, anti-tumor-promoter

  Publication DOI: 10.1080/10575630008041225
  Journal NLM ID: 9315615
  Publisher: Taylor & Francis Health Sciences
  Institutions: Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan, Faculty of Pharmacy, Meijo University, Nagoya, Japan, Department of Biochemistry, Kyoto Prefectural University of Medicine, Kyoto, Japan
  Methods: biological assays
  
   
  
  Carthamus tinctorius, Gossypium hirsutum
  CSDB ID 67034 (all data & tools)