Four new 3,4-seco-lupane-type triterpene glycosides (1−4) were isolated from the leaves of Acanthopanax senticosus forma inermis. The structures of 1−4 were established as 11α-hydroxy-3,4-seco-lup-4(23),20(30)-dien-3-oic acid methyl ester 28-oic acid 28-O-α-l-rhamnopyranosyl-(1→4)-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside, designated as inermoside (1); 1-deoxychiisanoside (2); 24-hydroxychiisanoside (3); and 11-deoxyisochiisanoside (4) by 1H− 1H COSY and 1H−13C COSY(HMBC, HMQC) methods and FABMS.
glycosides, Acanthopanax senticosus f. inermis, seco-lupane-type triterpenes
NCBI PubMed ID: 11141103Publication DOI: 10.1021/np000277cJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Park S-Y <996p9052@pharm.stud.kumamoto-u.ac.jp>
Institutions: Faculty of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan, College of Pharmacy, Kyung-Hee University, Seoul, South Korea, Korea Food and Drug Administration, Seoul, South Korea
Methods: 13C NMR, 1H NMR, EI-MS, NMR-2D, TLC, HPLC, extraction, evaporation, centrifugation, HR-EI-MS
Found