Two novel diglycosylated steroidal alkaloids of 5-pregnene nucleus, named obtusine-20(R)-O-[β-thevetopyranosyl-(1→4)-β-cymaropyranoside] and obtusolactam-20(R)-O-[β-thevetopyranosyl-(1→4)-β-cymaropyranoside], together with the known β-sitosteryl-3-O-β-glucopyranoside were isolated from the roots of Cryptolepis obtusa N. E. Br.
saponins, Cryptolepis obtusa, Periplocaceae or Asclepiadaceae, 5Δ-pregnene steroidal alkaloids
NCBI PubMed ID: 10703068Publication DOI: 10.1016/s0031-9422(99)00568-3Journal NLM ID: 0151434Publisher: Elsevier
Correspondence: peter.houghton@kcl.ac.uk
Institutions: CECF-Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, Centro de Quimica Organica ''Manuel Lora Tamayo'', Madrid, Spain, Pharmacognosy Research Laboratories, King's College London, London, UK
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, HPLC, extraction, evaporation
Found