Five triterpenoid saponins [buddlejasaponin IV, sandrosaponins VII (1), VIII (2), IX (3), and X (4)] were isolated from an n-BuOH extract of the roots of Bupleurum rigidum. Sandrosaponins VII-X (1-4) are new compounds, and their structures were established by 1D and 2D NMR techniques, FABMS, and chemical methods.
saponins, Bupleurum rigidum, buddlejasaponin IV, sandrosaponins VII-X
NCBI PubMed ID: 11087587Publication DOI: 10.1021/np000004hJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Díaz-Lanza AM
Institutions: Departamento de Química Orgánica Biológica, Instituto de Química Orgánica General, CSIC, Madrid, Spain, Laboratorio de Farmacognosia, Departamento de Farmacología, Facultad de Farmacia, Universidad de Alcalá de Henares, Alcalá de Henares, Spain
Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, TLC, ESI-MS, HPLC, extraction, CC
Found