The structures of two novel glycodienoid alkaloids isolated from Erythrina latissima seeds have been established as (+)-16β-d-glucoerysopine (1) and (+)-15β-d-glucoerysopine (2). NOE measurements established that 1 and 2 are positional isomers. Their structures were elucidated from their 1D and 2D homonuclear and heteronuclear NMR spectroscopic data. In addition, seven known tetracyclic dienoid alkaloids were isolated and identified as (+)-erysovine, (+)-erysodine, (+)-erysotrine, (+)-erythraline, (+)-β-d-glucoerysodine, (+)-8-oxoerythraline, and (+)-erysotramidine.
glycosides, alkaloids, Erythrina latissima, erysopine
NCBI PubMed ID: 10869225Publication DOI: 10.1021/np990540dJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: majindar@mopipi.ub.bw
Institutions: Department of Chemistry, University of Botswana, Gaborone, Botswana
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, HPLC, extraction, CC, HR-ESI-MS, evaporation, centrifugation
Found