Thirty new steroidal glycosides were obtained from the aerial part of Asclepias incarnata L. (Asclepiadaceae). These glycosides were confirmed to have lineolon, isolineolon, 12-O-acetyllineolon, 12-O-(Z)-cin-namoyllineolon, metaplexigenin, 15β-hydroxylineolon, 15β-hydroxyisolineolon, 16α-hydroxyisolineolon, 12-O-tigloyl-16α-hydroxyisolineolon as the aglycone and 2, 6-dideoxyhexoprranose as the sugar sequence by spectroscopic methods and chemical evidence.
2, Asclepiadaceae, 6-dideoxyhexopyranose, Asclepias incarnata, pregnane glycosice
NCBI PubMed ID: 10705484Publication DOI: 10.1248/cpb.48.99Journal NLM ID: 0377775Publisher: Pharmaceutical Society Of Japan
Institutions: Institute for Environmental Sciences, University of Shizuoka, Shizuoka, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, ESI-MS, acid hydrolysis, HPLC, extraction, CC, HR-ESI-MS, evaporation, centrifugation