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Found 2 structures. Displayed structures from 1 to 2
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1. Compound ID: 33318

Compound 33318

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Structure type: monomer
Compound class: glycoside

The structure is contained in the following publication(s):

Article ID: 12831
Wilson ID "Multiple hyphenation of liquid chromatography with nuclear magnetic resonance spectroscopy, mass spectrometry and beyond" - Journal of Chromatography A 892(1-2) (2000) 315-327

The advent of sensitive and reliable HPLC-NMR and HPLC-MS systems has revolutionised the identification of compounds eluting from chromatographic systems. More recently systems have been described wherein both NMR and MS are used together to provide an immensely powerful means of characterising compounds in chromatographic eluents. Here the construction and application of combined HPLC-NMR-MS systems to the analysis of mixtures of pharmaceuticals, drug metabolites in biological fluids and natural products in plant extracts is reviewed. In addition preliminary work with alternative systems such as HPLC-UV-NMR-FTIR-MS is highlighted and the prospects for such complex systems considered.
multiple hyphenation; complex mixture analysis; reviews
NCBI PubMed ID: 11045496
Publication DOI: 10.1016/s0378-4347(00)00071-2
Journal NLM ID: 9318488
Publisher: Amsterdam; New York: Elsevier
Correspondence: ian.wilson@astrazeneca.com
Institutions: Drug Metabolism and Pharmacokinetics Department, AstraZeneca Pharmaceuticals, Macclesfield, UK
Methods: 1H NMR, IR, MS, HPLC, extraction, 19F NMR, HPLC-NMR-MS, SEC-NMR-IR

Hypericum perforatum
CSDB ID 68619 (all data & tools)

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2. Compound ID: 33320

Compound 33320

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Structure type: monomer
Compound class: glycoside

The structure is contained in the following publication(s):

Article ID: 12831
Wilson ID "Multiple hyphenation of liquid chromatography with nuclear magnetic resonance spectroscopy, mass spectrometry and beyond" - Journal of Chromatography A 892(1-2) (2000) 315-327

The advent of sensitive and reliable HPLC-NMR and HPLC-MS systems has revolutionised the identification of compounds eluting from chromatographic systems. More recently systems have been described wherein both NMR and MS are used together to provide an immensely powerful means of characterising compounds in chromatographic eluents. Here the construction and application of combined HPLC-NMR-MS systems to the analysis of mixtures of pharmaceuticals, drug metabolites in biological fluids and natural products in plant extracts is reviewed. In addition preliminary work with alternative systems such as HPLC-UV-NMR-FTIR-MS is highlighted and the prospects for such complex systems considered.
multiple hyphenation; complex mixture analysis; reviews
NCBI PubMed ID: 11045496
Publication DOI: 10.1016/s0378-4347(00)00071-2
Journal NLM ID: 9318488
Publisher: Amsterdam; New York: Elsevier
Correspondence: ian.wilson@astrazeneca.com
Institutions: Drug Metabolism and Pharmacokinetics Department, AstraZeneca Pharmaceuticals, Macclesfield, UK
Methods: 1H NMR, IR, MS, HPLC, extraction, 19F NMR, HPLC-NMR-MS, SEC-NMR-IR

Hypericum perforatum
CSDB ID 68621 (all data & tools)

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