Four new oleanane-type triterpene glycosides, madlongisides A−D (1−4), were isolated from the seeds of Madhuca longifolia, and their structures were elucidated on the basis of extensive NMR experiments and chemical methods. Also obtained in this investigation were the known compounds mimusopside A, Mi-saponins A, B, and C, and 3-O-β-d-glucopyranosyl protobassic acid.
triterpene glycosides, Madhuca longifolia, Bassia longifolia, madlongisides A-D
NCBI PubMed ID: 11141115Publication DOI: 10.1021/np000351rJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: yosikawa@ph.bunri-u.ac.jp
Institutions: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan, Medicinal Chemistry Division, Indian Institute of Chemical Biology, Jadavpur, India, Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, Osaka, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, enzymatic hydrolysis, acid hydrolysis, HPLC, optical rotation measurement, HR-FAB-MS
Found