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Knirel YA, Dentovskaya SV, Bystrova OV, Kocharova NA, Senchenkova SN, Shaikhutdinova RZ, Titareva GM, Bakhteeva IV, Lindner B, Pier GB, Anisimov AP
Relationship of the lipopolysaccharide structure of Yersinia pestis to resistance to antimicrobial factors
Advances in Experimental Medicine and Biology 603 (2007) 88-96
 

Disruption of lipopolysaccharide (LPS) biosynthesis genes in an epidemiologically significant Yersinia pestis strain showed that the ability to synthesize the full inner core of the LPS is crucial for resistances to the bactericidal action of antimicrobial peptides and to complement-mediated serum killing. Resistance to polymyxin B also requires a high content of the cationic sugar, 4-amino-4-deoxy-L-arabinose, in lipid A.

function, lipopolysaccharide structure, Yersinia, Yersinia pestis, Polymyxin B

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