Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Organ / tissue: cell wall
NCBI PubMed ID: 34419536Publication DOI: 10.1016/j.ijbiomac.2021.08.101Journal NLM ID: 7909578Publisher: Butterworth-Heinemann
Correspondence: Liu G-K <liuguoku
hebau.edu.cn>; Wang J-R <wangjunru
nwafu.edu.cn>
Institutions: College of Agronomy, Hebei Agricultural University, Baoding, China, College of Chemistry & Pharmacy, Northwest A & F University, Shaanxi, China
Polyporus umbellatus (Pers.) Fries, a well-known medicinal fungus, has been reported to exhibit important functions of diuresis and dampness infiltration in traditional Chinese Medicine. Accumulating evidences have demonstrated that the P. umbellatus polysaccharides (PUPs) are the main and representative pharmacologically active ingredients and display multiple bioactivities both in vivo and in vitro methods, such as those of antioxidant, immunomodulatory, antitumor, anti-proliferative and hepatoprotective. Besides, many PUPs have been isolated from the different sources of P. umbellatus, including sclerotia, fruiting body, mycelia and fermentation liquid of this fungus. The purpose of the present review is to comprehensively and systematically reorganize the available information related to the extraction, purification, modification, structure characterization and to discuss diverse biological activities of PUPs to support their potential application value in pharmaceuticals field, functional foods and cosmetics areas. In addition, new invaluable insights on the future research with PUPs have also been proposed in the important areas of structural characterization and pharmacological activities.
polysaccharides, modification, bioactivities, Polyporus umbellatus, structural features, extraction methods
Structure type: homopolymer
Location inside paper: Fig. 2, F
Compound class: polysaccharide, sulfoglucan
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Comments, role: review
Related record ID(s): 41003, 41004, 41005
NCBI Taxonomy refs (TaxIDs): 158314
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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