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Taxonomic group: fungi / Basidiomycota (Phylum: Basidiomycota)
Organ / tissue: fruiting body

The structure was elucidated in this paper
NCBI PubMed ID: 38569989
Publication DOI: 10.1016/j.ijbiomac.2024.131320
Journal NLM ID: 7909578
Publisher: Butterworth-Heinemann
Correspondence: Xu J <xujing611

nankai.edu.cn>; Guo Y <victgyq

nankai.edu.cn>
Institutions: State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China, Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, China

Macrofungi, a class of unique natural resources, are gaining popularity owing to their potential therapeutic benefits and edibility. From Fomitopsis officinalis, a medicinal macrofungus with anticancer activity, a homogeneous heteropolysaccharide (FOBP50-1) with a molecular weight of 22100 g/mol has been extracted and purified. FOBP50-1 was found to be composed of 3-O-methylfucose, fucose, mannose, glucose, and galactose with a ratio of 1: 6.5: 4.4: 8.1: 18.2. The sugar fragments and structure of FOBP50-1 were investigated, which included→6)-α-d-Galp-(1→,→2,6)-α-d-Galp-(1→,→3)-α-l-Fucp-(1→, α-d-Glcp-(1→,→3)-β-d-Manp-(1→,→6)-β-d-Manp-(1→, 3-O-Me-α-l-Fucp-(1→, according to the UV, FT-IR, GC-MS, and NMR data. Besides the structure elucidation, FOBP50-1 showed promising antitumor activity in the zebrafish assays. The following mechanism examination discovered that FOBP50-1 interacted with TLR-4, PD-1, and VEGF to activate immunity and inhibit angiogenesis according to a series of cell, transgenic zebrafish, and surface plasmon resonance (SPR) experiments. The KD values indicating the association of FOBP50-1 with TLR-4, PD-1, and VEGF, were 46.9, 7.98, 3.04 μM, respectively, in the SPR experiments. All investigations have demonstrated that the homogenous fungal polysaccharide FOBP50-1 has the potential to be turned into a tumor immunotherapy agent

angiogenesis, immune activation, Fomitopsis officinalis, cancer treatment, VEGF, PD-1

Structure type: structural motif or average structure ; 22100
Location inside paper: Fig. 4, Table 3
Compound class: polysaccharide
Contained glycoepitopes: IEDB_134624,IEDB_136045,IEDB_136906,IEDB_137472,IEDB_137485,IEDB_141794,IEDB_142488,IEDB_142489,IEDB_144562,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_152206,IEDB_152214,IEDB_153553,IEDB_174333,IEDB_190606,IEDB_983930,IEDB_983931,SB_154,SB_163,SB_192,SB_44,SB_7,SB_72,SB_86

Methods: 13C NMR, 1H NMR, NMR-2D, GC-MS, acid hydrolysis, biological assays, extraction, acetylation, methylation analysis, reduction, dialysis, precipitation, centrifugation, FT-IR, fractionation, Congo red test
Biological activity: compound was discovered to have potent anticancer efficacy in vivo. The potential anticancer mechanism was revealed to be connected to research foci in cancer biology, such as immune activation and angiogenesis inhibition, which discovered this compound to associate with PD-1/VEGF/TLR-4 to produce antitumor action

NCBI Taxonomy refs (TaxIDs): 270279
Show glycosyltransferases

NMR conditions: in D2O [as TSV]

13C NMR data:
Linkage	Residue	C1	C2	C3	C4	C5	C6
6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,2,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,2	aLFucp
6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6,6,6,6,6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,6,6,6,6,2,6,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,6,6,6,6,2,6	aLFucp
6,6,6,6,6,6,2	bDManp
6,6,6,6,6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6,6,6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,6,6,2,6,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,6,6,2,6	aLFucp
6,6,6,6,2	bDManp
6,6,6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
2,3	Me	56.1
2	aLFucp	101.4	68.3	78.6	69.6	67.9	15.6
	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4


1H NMR data:
Linkage	Residue	H1	H2	H3	H4	H5	H6
6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79-3.85
6,6,2,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75-3.86
6,6,2	aLFucp
6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72-3.86
6,6,6,6,6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79-3.85
6,6,6,6,6,6,2,6,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75-3.86
6,6,6,6,6,6,2,6	aLFucp
6,6,6,6,6,6,2	bDManp
6,6,6,6,6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72-3.86
6,6,6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79-3.85
6,6,6,6,2,6,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75-3.86
6,6,6,6,2,6	aLFucp
6,6,6,6,2	bDManp
6,6,6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72-3.86
6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79-3.85
2,3	Me	3.43
2	aLFucp	5.04	3.82	3.56	3.65	4.10	1.20
	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72-3.86


1H/13C HSQC data:
Linkage	Residue	C1/H1	C2/H2	C3/H3	C4/H4	C5/H5	C6/H6
6,6,6	aDGalp	102.4/5.08	67.6/3.95	68.1/3.86	71.7/3.80	70.8/3.57	66.1/3.79-3.85
6,6,2,3	aDGlcp	98.1/4.96	68.7/3.81	69.5/3.99	66.7/3.87	71.3/3.96	60.1/3.75-3.86
6,6,2	aLFucp
6,6	aDGalp	101.3/5.09	77.5/3.81	69.2/3.56	67.1/4.12	72.1/3.71	66.4/3.72-3.86
6,6,6,6,6,6,6	aDGalp	102.4/5.08	67.6/3.95	68.1/3.86	71.7/3.80	70.8/3.57	66.1/3.79-3.85
6,6,6,6,6,6,2,6,3	aDGlcp	98.1/4.96	68.7/3.81	69.5/3.99	66.7/3.87	71.3/3.96	60.1/3.75-3.86
6,6,6,6,6,6,2,6	aLFucp
6,6,6,6,6,6,2	bDManp
6,6,6,6,6,6	aDGalp	101.3/5.09	77.5/3.81	69.2/3.56	67.1/4.12	72.1/3.71	66.4/3.72-3.86
6,6,6,6,6	aDGalp	102.4/5.08	67.6/3.95	68.1/3.86	71.7/3.80	70.8/3.57	66.1/3.79-3.85
6,6,6,6,2,6,3	aDGlcp	98.1/4.96	68.7/3.81	69.5/3.99	66.7/3.87	71.3/3.96	60.1/3.75-3.86
6,6,6,6,2,6	aLFucp
6,6,6,6,2	bDManp
6,6,6,6	aDGalp	101.3/5.09	77.5/3.81	69.2/3.56	67.1/4.12	72.1/3.71	66.4/3.72-3.86
6	aDGalp	102.4/5.08	67.6/3.95	68.1/3.86	71.7/3.80	70.8/3.57	66.1/3.79-3.85
2,3	Me	56.1/3.43
2	aLFucp	101.4/5.04	68.3/3.82	78.6/3.56	69.6/3.65	67.9/4.10	15.6/1.20
	aDGalp	101.3/5.09	77.5/3.81	69.2/3.56	67.1/4.12	72.1/3.71	66.4/3.72-3.86

¹H NMR data:

Linkage	Residue	H1	H2	H3	H4	H5	H6
6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79 3.85
6,6,2,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75 3.86
6,6,2	aLFucp
6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72 3.86
6,6,6,6,6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79 3.85
6,6,6,6,6,6,2,6,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75 3.86
6,6,6,6,6,6,2,6	aLFucp
6,6,6,6,6,6,2	bDManp
6,6,6,6,6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72 3.86
6,6,6,6,6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79 3.85
6,6,6,6,2,6,3	aDGlcp	4.96	3.81	3.99	3.87	3.96	3.75 3.86
6,6,6,6,2,6	aLFucp
6,6,6,6,2	bDManp
6,6,6,6	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72 3.86
6	aDGalp	5.08	3.95	3.86	3.80	3.57	3.79 3.85
2,3	Me	3.43
2	aLFucp	5.04	3.82	3.56	3.65	4.10	1.20
	aDGalp	5.09	3.81	3.56	4.12	3.71	3.72 3.86

¹³C NMR data:

Linkage	Residue	C1	C2	C3	C4	C5	C6
6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,2,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,2	aLFucp
6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6,6,6,6,6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,6,6,6,6,2,6,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,6,6,6,6,2,6	aLFucp
6,6,6,6,6,6,2	bDManp
6,6,6,6,6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6,6,6,6,6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
6,6,6,6,2,6,3	aDGlcp	98.1	68.7	69.5	66.7	71.3	60.1
6,6,6,6,2,6	aLFucp
6,6,6,6,2	bDManp
6,6,6,6	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4
6	aDGalp	102.4	67.6	68.1	71.7	70.8	66.1
2,3	Me	56.1
2	aLFucp	101.4	68.3	78.6	69.6	67.9	15.6
	aDGalp	101.3	77.5	69.2	67.1	72.1	66.4

There is only one chemically distinct structure:

*OC[C@H]1O[C@H](OC[C@H]2O[C@H](OC[C@H]3O[C@H](OC[C@H]4O[C@H](OC[C@H]5O[C@H](OC[C@H]6O[C@H](OC[C@H]7O[C@H](OC[C@H]8O[C@H](OC[C@H]9O[C@H](OC[C@H]%10O[C@H](OC[C@H]%11O[C@H](OC[C@H]%12O[C@H](OC[C@H]%13O[C@H](OC[C@H]%14O[C@H](OC[C@H]%15O[C@H](OC[C@H]%16O[C@H](*)[C@H](O[C@@H]%17O[C@@H](C)[C@@H](O)[C@@H](OC)[C@@H]%17O)[C@@H](O)[C@H]%16O)[C@H](O)[C@@H](O)[C@H]%15O)[C@H](O[C@@H]%15O[C@@H](C)[C@@H](O)[C@@H](O[C@H]%16O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%16O)[C@@H]%15O)[C@@H](O)[C@H]%14O)[C@H](O)[C@@H](O)[C@H]%13O)[C@H](O[C@@H]%13O[C@@H](C)[C@@H](O)[C@@H](O[C@H]%14O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%14O)[C@@H]%13O)[C@@H](O)[C@H]%12O)[C@H](O)[C@@H](O)[C@H]%11O)[C@H](O[C@@H]%11O[C@@H](C)[C@@H](O)[C@@H](O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)[C@@H]%11O)[C@@H](O)[C@H]%10O)[C@H](O)[C@@H](O)[C@H]9O)[C@H](O[C@@H]9O[C@@H](C)[C@@H](O)[C@@H](O[C@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H]9O)[C@@H](O)[C@H]8O)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H]7O)[C@@H](O)[C@H]6O)[C@H](O)[C@@H](O)[C@H]5O)[C@H](O[C@@H]5O[C@H](CO[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O[C@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H]6O)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H]4O)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

SVG MW SMILES 3D mol Ionize

Warning = sub-repeat ending at aDGalp: large unit count (7) was reduced to 5

Taxonomic group: fungi / Basidiomycota (Phylum: Basidiomycota)
Organ / tissue: fruiting body

NCBI PubMed ID: 39276254
Publication DOI: 10.1007/s13659-024-00476-6
Journal NLM ID: 101577734
Publisher: Heidelberg: Springer
Correspondence: Yang L <yangliu

mail.kib.ac.cn>; Hu JM <hujiangmiao

mail.kib.ac.cn>
Institutions: University of Chinese Academy of Sciences, Beijing, China, Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China

Dictyophora rubrovalvata is a valuable fungus homologous to food and medicine, and its polysaccharide have been gaining increasing attention because of its plentiful activity. However, the structure and activity of its homogeneous polysaccharide have not been studied enough. In this study, two polysaccharides DRP-I and DRP-II were purified from D. rubrovalvata. Their structures were characterized by chemical composition, monosaccharide composition analysis, methylation analysis and nuclear magnetic resonance spectroscopy. The results showed that DRP-I and DRP-II were neutral heteropolysaccharides with molecular weights of 5790 and 12500 Da, respectively, which were composed of mannose, galactose, glucose, xylose and fucose. The main chains were→6)-α-D-Galp-(1→6)-α-D-Galp-(2,1→6)-α-D-Manp-(2,1→6)-α-D-Galp-(1, and branch chains were β-D-Xylp-(1→3)-α-L-Fucp-(1→4)-α-D-Manp-(1→and α-D-Galp-(1→3)-α-D-Galp-(1→. The in vitro immunoactivity assays on dendritic cells showed that DRP-I and DRP-II could up-regulate the expression of IL-10 and IL-6 and inhibit the expression of TNF-α in a concentration-dependent manner. This research indicated that DRP-I and DRP-II possessed immunoactivity by balancing the excessive inflammation, and molecular weight is an important factor affecting immunoactivity

polysaccharides, structure characterization, immunoactivity, Dictyophora rubrovalvata

Structure type: structural motif or average structure ; 5790
Location inside paper: Fig. 3, Table 3
Compound class: polysaccharide
Contained glycoepitopes: IEDB_114701,IEDB_130701,IEDB_134624,IEDB_136045,IEDB_136906,IEDB_137472,IEDB_141794,IEDB_142489,IEDB_144562,IEDB_144983,IEDB_151528,IEDB_152206,IEDB_152214,IEDB_167188,IEDB_174332,IEDB_174333,IEDB_190606,IEDB_983930,SB_163,SB_44,SB_67,SB_7,SB_72,SB_86

Methods: 13C NMR, 1H NMR, NMR-2D, ELISA, acid hydrolysis, biological assays, HPLC, GPC, UV, extraction, acetylation, methylation analysis, reduction, precipitation, phenol-sulfuric acid assay, SEM, derivatization, Sevag method, centrifugation, HPLC-ELSD, FT-IR, proliferation assay, Congo red test, bicinchoninic acid assay
Biological activity: compound could up-regulate the expression of IL-10 and IL-6 and inhibit the expression of TNF-α in a concentration-dependent manner

NCBI Taxonomy refs (TaxIDs): 1464785
Show glycosyltransferases

NMR conditions: in D2O [as TSV]

13C NMR data:
Linkage	Residue	C1	C2	C3	C4	C5	C6
6,6,6,6	aDGalp	97.81-97.86	68.25	69.46	68.21	68.78	66.44
6	aDGalp	97.81-97.86	68.25	69.46	68.21	68.78	66.44
6,6,6,2,3	aDManp	98.20	70.37	72.87	66.75	76.22	61.02
6,6,6,2	aDGalp	102.40	69.78	77.57	72.54	68.78	61.02
6,6,6	aDManp	98.30	76.95	70.99	?	?	66.44
6,6,2,4,3	bDXylp	104.43	73.02	75.65	69.20	65.06
6,6,2,4	aLFucp	101.67	70.37	77.57	73.35	67.19	15.19
6,6,2	aDManp	101.47	68.80	68.25	71.69	?	?
6,6	aDGalp	97.99	78.05	68.25	67.49	68.25	66.44
	aDGalp	97.81-97.86	68.25	69.46	68.21	68.78	66.44


1H NMR data:
Linkage	Residue	H1	H2	H3	H4	H5	H6
6,6,6,6	aDGalp	5.00-5.02	3.84	4.02	3.89	4.20	3.68-3.91
6	aDGalp	5.00-5.02	3.84	4.02	3.89	4.20	3.68-3.91
6,6,6,2,3	aDManp	5.13	4.11	3.66	3.60	3.38	3.75-3.93
6,6,6,2	aDGalp	5.11	4.08	4.00	3.90	4.16	3.75-3.89
6,6,6	aDManp	5.14	3.94	4.02	?	?	3.72-3.87
6,6,2,4,3	bDXylp	4.61	3.32	3.45	3.63	3.33-3.96
6,6,2,4	aLFucp	5.09	3.90	4.08	3.77	4.18	1.23
6,6,2	aDManp	5.07	3.79	3.90	3.84	?	?
6,6	aDGalp	5.06	3.82	4.06	3.97	3.85	3.72-3.87
	aDGalp	5.00-5.02	3.84	4.02	3.89	4.20	3.68-3.91


1H/13C HSQC data:
Linkage	Residue	C1/H1	C2/H2	C3/H3	C4/H4	C5/H5	C6/H6
6,6,6,6	aDGalp	97.81-97.86/5.00-5.02	68.25/3.84	69.46/4.02	68.21/3.89	68.78/4.20	66.44/3.68-3.91
6	aDGalp	97.81-97.86/5.00-5.02	68.25/3.84	69.46/4.02	68.21/3.89	68.78/4.20	66.44/3.68-3.91
6,6,6,2,3	aDManp	98.20/5.13	70.37/4.11	72.87/3.66	66.75/3.60	76.22/3.38	61.02/3.75-3.93
6,6,6,2	aDGalp	102.40/5.11	69.78/4.08	77.57/4.00	72.54/3.90	68.78/4.16	61.02/3.75-3.89
6,6,6	aDManp	98.30/5.14	76.95/3.94	70.99/4.02	?/?	?/?	66.44/3.72-3.87
6,6,2,4,3	bDXylp	104.43/4.61	73.02/3.32	75.65/3.45	69.20/3.63	65.06/3.33-3.96
6,6,2,4	aLFucp	101.67/5.09	70.37/3.90	77.57/4.08	73.35/3.77	67.19/4.18	15.19/1.23
6,6,2	aDManp	101.47/5.07	68.80/3.79	68.25/3.90	71.69/3.84	?/?	?/?
6,6	aDGalp	97.99/5.06	78.05/3.82	68.25/4.06	67.49/3.97	68.25/3.85	66.44/3.72-3.87
	aDGalp	97.81-97.86/5.00-5.02	68.25/3.84	69.46/4.02	68.21/3.89	68.78/4.20	66.44/3.68-3.91

¹H NMR data:

Linkage	Residue	H1	H2	H3	H4	H5	H6
6,6,6,6	aDGalp	5.00 5.02	3.84	4.02	3.89	4.20	3.68 3.91
6	aDGalp	5.00 5.02	3.84	4.02	3.89	4.20	3.68 3.91
6,6,6,2,3	aDManp	5.13	4.11	3.66	3.60	3.38	3.75 3.93
6,6,6,2	aDGalp	5.11	4.08	4.00	3.90	4.16	3.75 3.89
6,6,6	aDManp	5.14	3.94	4.02	?	?	3.72 3.87
6,6,2,4,3	bDXylp	4.61	3.32	3.45	3.63	3.33 3.96
6,6,2,4	aLFucp	5.09	3.90	4.08	3.77	4.18	1.23
6,6,2	aDManp	5.07	3.79	3.90	3.84	?	?
6,6	aDGalp	5.06	3.82	4.06	3.97	3.85	3.72 3.87
	aDGalp	5.00 5.02	3.84	4.02	3.89	4.20	3.68 3.91

¹³C NMR data:

Linkage	Residue	C1	C2	C3	C4	C5	C6
6,6,6,6	aDGalp	97.81 97.86	68.25	69.46	68.21	68.78	66.44
6	aDGalp	97.81 97.86	68.25	69.46	68.21	68.78	66.44
6,6,6,2,3	aDManp	98.20	70.37	72.87	66.75	76.22	61.02
6,6,6,2	aDGalp	102.40	69.78	77.57	72.54	68.78	61.02
6,6,6	aDManp	98.30	76.95	70.99	?	?	66.44
6,6,2,4,3	bDXylp	104.43	73.02	75.65	69.20	65.06
6,6,2,4	aLFucp	101.67	70.37	77.57	73.35	67.19	15.19
6,6,2	aDManp	101.47	68.80	68.25	71.69	?	?
6,6	aDGalp	97.99	78.05	68.25	67.49	68.25	66.44
	aDGalp	97.81 97.86	68.25	69.46	68.21	68.78	66.44

The spectrum also has 4 signals at unknown positions (not plotted).

There is only one chemically distinct structure:

*OC[C@H]1O[C@H](OC[C@H]2O[C@H](OC[C@H]3O[C@H](OC[C@H]4O[C@H](OC[C@H]5O[C@H](OC[C@H]6O[C@H](OC[C@H]7O[C@H](OC[C@H]8O[C@H](OC[C@H]9O[C@H](*)[C@H](O)[C@@H](O)[C@H]9O)[C@H](O)[C@@H](O)[C@H]8O)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@@H](O)[C@H]6O)[C@H](O[C@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@@H](O)[C@@H](O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O)[C@@H]7O)[C@H](O)[C@@H]6O)[C@@H](O)[C@H]5O)[C@@H](O[C@H]5O[C@H](CO)[C@H](O)[C@H](O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@H]5O)[C@@H](O)[C@@H]4O)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

SVG MW SMILES 3D mol Ionize

Warning = sub-repeat ending at aDGalp: unknown unit count was assumed to be 3
Warning = sub-repeat ending at aDGalp: unknown unit count was assumed to be 3