Liu JJ, Hou YK, Wang X, Zhou XT, Yin JY, Nie SP Recent advances in the biosynthesis of fungal glucan structural diversity Carbohydrate Polymers329 (2024)
ID 121782
NCBI PubMed ID:38286552 Publication DOI:10.1016/j.carbpol.2024.121782 Journal NLM ID:8307156 Publisher: Elsevier Correspondence: Yin JY <yinjyncu.edu.cn>; Nie SP <spniencu.edu.cn> Institutions: State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Nanchang University, Nanchang, China, Food Laboratory of Zhongyuan, Henan, China
Glucans are the most abundant class of macromolecule polymers in fungi, which are commonly found in Ascomycota and Basidiomycota. Fungal glucans are not only essential for cell integrity and function but also crucial for the immense industrial interest in high value applications. They present a variety of structural characteristics at the nanoscale due to the high regulation of genes and the involvement of stochastic processes in synthesis. However, although recent findings have demonstrated the genes of glucans synthesis are relatively conserved across diverse fungi, the formation and organization of diverse glucan structures is still unclear in fungi. Here, we summarize the structural features of fungal glucans and the recent developments in the mechanisms of glucans biosynthesis. Furthermore, we propose the engineering strategies of targeted glucan synthesis and point out the remaining challenges in the synthetic process. Understanding the synthesis process of diverse glucans is necessary for tailoring high value glucan towards specific applications. This engineering strategy contributes to enable the sustainable and efficient production of glucan diversity
Lu R, Miyakoshi T, Tian G, Yoshida T Structural studies of Paecilomyces tenuipes Samson polysaccharide-part-2 Carbohydrate Polymers67(3) (2007)
343-346
/Variants 0/-+
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-6)-b-D-Glcp-(1-
/Variants 0/ is:
50%b-D-Manp-(1-4)-
OR (exclusively)
50%b-D-Galp-(2-4)-
The structure was elucidated in this paper Publication DOI:10.1016/j.carbpol.2006.06.003 Journal NLM ID:8307156 Publisher: Elsevier Correspondence: lurongisc.meiji.ac.jp Institutions: Department of Industrial Chemistry, School of Science and Technology, Meiji University, Kawasaki-shi, Japan, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China, Applied Chemistry Department, Kitami Institute of Technology, Kitami, Japan
A water-soluble polysaccharide-part-2 separated from Paecilomyces tenuipes Samson was determined to be homogeneous by gel permeation chromatography (GPC). HPLC showed a monosaccharide containing d-glucose, d-galactose, and d-mannose at a ratio of about 2:1:1. The number-average molecular weight was estimated to be 10200. The specific rotation was determined to be [α]D2O = + 54 °. The GC-MS analysis of hydrolysates obtained from acid-catalyzed hydrolysis of both Paecilomyces tenuipes Samson-part-2 and its methylated product showed that it has a β-(1→6)-d-glucose main chain with β-(1→6)-d-mannose and β-(2→6)-d-galactose side chains. The results obtained from IR, 1H NMR, and 13C NMR analyses confirmed the proposed structure.
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(later renamed to: Macrocybe crassa)
ncu.edu.cn>; Nie SP <spnie