report error
Found 4 records.
Displayed records from 1 to 4
|
1. (CSDB ID: 42690) | report error |
| -3)-a-D-Glcp-(1- | Show graphically |
|
Show legend Show as text |
Poria cocos
(later renamed to: Wolfiporia cocos)
(NCBI TaxID 81056,
species name lookup)
public.wh.hb.cn>A water-insoluble (1→3)-α-D-glucan from Poria cocos mycelia was fractionated, followed by phosphorylation with H3PO4 in LiCl/Me2SO containing urea to synthesize water-soluble phosphated derivatives. Their structures and chain conformations were investigated by FTIR, 31P NMR, SEC-LLS and viscometry. The Mark-Houwink equation for the phosphated derivative in 0.15 M aqueous NaCl at 30 °C was established to be [η]=2.87*10^-3 Mw 0.86±0.02. On the basis of conformational parameters calculated from wormlike cylinder model, the phosphated derivative existed as a semi-stiff chain in aqueous solution. Compared with unphosphated glucan, water-solubility and chain stiffness of the phosphated derivative increased, as a result of the introduction of phosphate group on main chain. All the phosphated derivatives exhibited significantly stronger anti-tumor activities than that of the unphosphated one, suggesting the effects of solubility and expanded chain conformation on improvement of the anti-tumor activity could not be negligible.
Chain conformation, (1→3)-α-D-glucan, anti-tumor activity, Poria cocos mycelia, phosphated derivative
Structure type: homopolymer ; 573000 (F1), 452000 (F2), 375000 (F3), 308000 (F4), 283000 (F5), 230000 (F6), 174000 (F7), 111000 (F8), 77400 (F9)|
2. (CSDB ID: 42691) | report error |
| ?%P-6)-+ | -3)-a-D-Glcp-(1- | Show graphically |
|
Show legend Show as text |
Poria cocos
(later renamed to: Wolfiporia cocos)
(NCBI TaxID 81056,
species name lookup)
public.wh.hb.cn>A water-insoluble (1→3)-α-D-glucan from Poria cocos mycelia was fractionated, followed by phosphorylation with H3PO4 in LiCl/Me2SO containing urea to synthesize water-soluble phosphated derivatives. Their structures and chain conformations were investigated by FTIR, 31P NMR, SEC-LLS and viscometry. The Mark-Houwink equation for the phosphated derivative in 0.15 M aqueous NaCl at 30 °C was established to be [η]=2.87*10^-3 Mw 0.86±0.02. On the basis of conformational parameters calculated from wormlike cylinder model, the phosphated derivative existed as a semi-stiff chain in aqueous solution. Compared with unphosphated glucan, water-solubility and chain stiffness of the phosphated derivative increased, as a result of the introduction of phosphate group on main chain. All the phosphated derivatives exhibited significantly stronger anti-tumor activities than that of the unphosphated one, suggesting the effects of solubility and expanded chain conformation on improvement of the anti-tumor activity could not be negligible.
Chain conformation, (1→3)-α-D-glucan, anti-tumor activity, Poria cocos mycelia, phosphated derivative
Structure type: structural motif or average structure ; 156000 (P1), 92900 (P2), 78700 (P3), 56700 (P4), 35000 (P5), 34500 (P6), 31400 (P7), 29800 (P8), 19600 (P9)|
3. (CSDB ID: 43850) | report error |
| /Variants 0/-+ | -6)-a-D-Manp-(1- /Variants 0/ is: 6%a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 13%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 19%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 14%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 10%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 5%a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)- OR (exclusively) 8%a-D-Manp-(1-2)- | Show graphically |
|
Show legend Show as text |
Lasallia pustulata
(later renamed to: Umbilicaria pustulata)
(NCBI TaxID 136370,
species name lookup)
cib.csic.esPolysaccharides from thalli of Lasallia pustulata were extracted and characterized. The major fractions were characterized as pustulan, a β-glucan–chitin complex and a β-(1→3)-glucan. Other polysaccharides, which are minor components (less than 5%) solubilized with water from the alkali extracts of thalli, were shown to be galactomannans with a backbone of α-(1→6)-mannose partially substituted at positions 2 by galactofuranose and/or mannopyranose side chains of variable length. The relationship between these polysaccharides and those obtained by the same method from free-living fungi is discussed. The proportion or composition of the different polysaccharides studied was not affected by seasonal environmental conditions over a 2-year period.
NMR spectroscopy, polysaccharides, Lasallia pustulata, mannan core
Structure type: structural motif or average structure|
4. (CSDB ID: 50072) | report error |
| b-D-Glcp-(1-6)-+ | -3)-b-D-Glcp-(1-3)-b-D-Glcp-(1-3)-b-D-Glcp-(1- | Show graphically |
|
Show legend Show as text |
Schizophyllum commune
(NCBI TaxID 5334,
species name lookup)
gmail.comThe use of natural polymers and electrospinning as a new method of wound dressing production is one of the things that can revolutionize the medical world. Due to the importance of wound healing and characteristics such as anti-inflammatory and antimicrobial properties, it is possible to use natural compounds such as fungi and metabolites derived from them to produce wound dressing. In this study, schizophyllan (SPG) as an extracellular polysaccharide was extracted from Iranian Schizophyllum commune (NCBI MG761830) and then the silver nanoparticles (AgNPs) were produced by the in-situ method in 1.5 % SPG solution. Afterward, they were combined with polyvinyl alcohol 10 % (PVA) polymer to strengthen the fiber structure. We investigated the properties of nanofibers containing PVA/SPG-AgNPs and PVA/SPG20 %. The physicochemical properties of two fibers were investigated by SEM, TEM, FTIR, contact angle, water uptake, nanoparticle release, and biological test (antibacterial, and MTT). The diameter of the nanofiber-containing the AgNPs was about 169 nm and the other nanofiber was about 212 nm. The highest inhibition of the growth of the bacterium by PVA/SPG-AgNPs against E. coli and S. aureus was about 88.34 % and 64.7 %, respectively. The silver ion release from PVA/SPG-AgNPs nanofibers was 21 μg/ml after fifth day. Both nanofibers had no toxic effect on L929 fibroblast cells.
cytotoxicity, in situ, schizophyllan, nanofiber, silver nanoparticle
Structure type: polymer chemical repeating unit| New query | Export IDs | Home | Help |
Execution: <1 sec