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Structure type: oligomer
Aglycon: phenolphthiocerol dimycocerosate
Compound class: glycolipid
Contained glycoepitopes: IEDB_128162,IEDB_128163,IEDB_128164,IEDB_131183,IEDB_133754,IEDB_134625,IEDB_136105,IEDB_137477,IEDB_142488,IEDB_146664,IEDB_225177,IEDB_885823,IEDB_983931,SB_192

• Article ID: 1685
  Jardine I, Scanlan G, McNeil M, Brennan PJ "Plasma desorption mass spectrometric analysis of mycobacterial glycolipids" - Analytical Chemistry 61 (1989) 416-422
  

  Mycobacteria are characterized by species- or type-specific glycolipid antigens. These are generally of the following three types: the trehalose-containing, acylated lipooligosaccharides (LOS), the C-mycoside glycopeptidolipids (GPL), and the phenolic glycolipids (PGL). To date, convenient mass spectrometric analysis of the intact form of these complex glycolipids has proved to be difficult. The successful plasma desorption mass spectrometric analysis of intact mycobacterial glycolipids of the LOS, GPL, and PGL types is now reported, allowing location of the acyl residues and providing oligosaccharide sequence and molecular weight information.

  NCBI PubMed ID: 2719255
  Publication DOI: 10.1021/ac00180a008
  Journal NLM ID: 0370536
  
   
  
  Mycobacterium leprae
  CSDB ID 103203 (all data & tools)
• Article ID: 1791
  Daffé M, Lanéelle MA "Diglycosyl phenol phthiocerol diester of Mycobacterium leprae" - Biochimica et Biophysica Acta 1002 (1989) 333-337
  
  Journal NLM ID: 0217513
  Publisher: Elsevier
  Methods: 1H NMR
  
   
  
  Mycobacterium leprae
  CSDB ID 109223 (all data & tools)
• Article ID: 1796
  Hartmann S, Minnikin DE, Mallet AI, Ridell M, Rigouts L, Portaels F "Fast atom bombardment mass spectrometry of mycobacterial phenolic glycolipids" - Biological Mass Spectrometry 23 (1994) 362-368
  

  Fast atom bombardment mass spectra were successfully recorded for intact glycosylphenolphthiocerol dimycocerosates (phenolic glycolipids, PGLs) from Mycobacterium kansasii, M. leprae, M. tuberculosis, M. marinum, M. bovis and M. haemophilum. Characteristic fragment ions from the loss of the oligosaccharide moiety and one of the long-chain multimethyl-branched mycocerosic acids were observed in most cases. A tandem mass spectrometric experiment was carried out on the PGL from M. tuberculosis, revealing the type of mycocerosic acids esterified to individual homologues. Mass spectra of homologues separated by reversed-phase high-performance liquid chromatography gave information on the substitution pattern in certain cases. The potential of matrix-assisted laser desorption ionization spectroscopy was demonstrated by a successful analysis of the PGL from M. tuberculosis.

  NCBI PubMed ID: 8038230
  Journal NLM ID: 9102982
  Institutions: Department of Chemistry, The University, Newcastle upon Tyne, UK
  Methods: FAB-MS
  
   
  
  Mycobacterium leprae
  CSDB ID 110032 (all data & tools)