Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: thallus
NCBI PubMed ID: 11345688Publication DOI: 10.1055/s-2001-12012Journal NLM ID: 0066751Publisher: George Thieme
Correspondence: Olafsdottir ES <elinsol
hi.is>
Institutions: Faculty of Pharmacy, University of Iceland, Reykjavik, Iceland
Lichens have been used for medicinal purposes throughout the ages, and beneficial claims have to some extent been correlated with their polysaccharide content. Of 13,500 lichen species growing worldwide, less than 100 species have been investigated for polysaccharide content. Lichen polysaccharides are mainly of three different structural types: β-glucans, α-glucans, and galactomannans. In addition, a few complex heteroglycans have recently been described, such as thamnolan, a water-soluble, immunologically active heteroglycan with a novel rhamnopyranosylgalactofuranan type of structure. A number of investigations have been carried out on biological effects of lichen polysaccharides, most notably antitumour, immunomodulating, antiviral, and memory-enhancing effects. The current review summarizes present knowledge on the structural characteristics and biological activity of lichen polysaccrides.
polysaccharides, biological activity, immunological activity, lichens, structural characteristics, antitumour activity
Structure type: homopolymer
Location inside paper: pustulan, table 1, table 2
Trivial name: pustulan, β-1,6-glucan, β-1,6-D-glucan, β(1-6)-D-glucan, β-(1,6)-glucan, lasiodiplodan, pustulan, β-(1,6)-glucan, lasiodiplodan, β-(1,6)-glucan, β-(1,6)-glucan, lasiodiplodan, pustulan, β-1,6-glucan, β-(1,6)-glucan, pustulan, β-(1→6)-glucan PCPS, water-soluble glucan (PS-I)
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, glycoprotein, glucan, polysaccharide, cell wall glucoprotein
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Biological activity: strong antiviral and antitumor activity
Comments, role: review; symbiotic organisms
Related record ID(s): 47187, 47189, 47190, 47191
NCBI Taxonomy refs (TaxIDs): 195753,
87280,
87267,
1217314,
580043,
283346,
136372,
136370Reference(s) to other database(s): GTC:G26777BZ, GlycomeDB:
863, CCSD:
50854, CBank-STR:4234
Show glycosyltransferases
[as TSV]
13C NMR data: present in publication
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There is only one chemically distinct structure:
Found 
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