Taxonomic group: bacteria, algae / Proteobacteria,
(Phylum: Proteobacteria, )
NCBI PubMed ID: 32138756Publication DOI: 10.1186/s13048-020-00626-7Journal NLM ID: 101474849Publisher: London: BioMed Central
Correspondence: Sadoughi F <rahasadoughi
gmail.com>; Asemi Z <asemi_r
yahoo.com>
Institutions: Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran, Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran, Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran, Student Research Committee, Faculty of Public Health Branch, Iran University of Medical Sciences, Tehran, Iran
Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying to discovery alternative therapies. β-glucans, a group of glucose polymers that are derived from the cell wall of fungi, bacteria, and etc. it has been showed that β-glucans have some anti-cancer properties which due to their impacts on adaptive and innate immunity. Along to these impacts, these molecules could be used as drug carriers. In this regard, the application of β-glucans is a promising therapeutic option for the cancer prevention and treatment especially for cervical cancer. Herein, we have summarized the therapeutic potential of β-glucans alone or as adjuvant therapy in the treatment of cervical cancer. Moreover, we highlighted β-glucans as drug carriers for preventive and therapeutic purposes.
bacteria, β-Glucans, fungi, cervical cancer
Structure type: homopolymer
Location inside paper: Table 1, curdlan, chrysolaminaran
Trivial name: glucan, β-1,3-glucan, curdlan, curdlan-type polysaccharide 13140, paramylon, curdlan, laminarin, β-glucan, curdlan, β-(1,3)-glucan, β-(1,3)-glucan, curdlan, curdlan, β-1,3-glucan, paramylon, reserve polysaccharide, b-glucan, β-1,3-D-glucan, laminaran, botryosphaeran, laminaran type β-D-glucan, latiglucan I, pachymaran, Curdlan, zymosan A, β-glucan, curdlan, laminarin, zymosan, zymosan, glucan particles, zymosan, β-(1-3)-glucan, β-(1,3)-glucan, β-(1,3)glucan, pachymaran, D-glucan (DPn)540, pachyman, laminaran, curdlan, zymosan, zymosan, β-(1,3)-glucan, zymosan A, zymosan, β-1,3-glucan, curdlan, β-1,3-glucan, curdlan, β-1,3-glucan, curdlan, pachyman, β-(1,3)-glucan, curdlan, callose, a water-insoluble β-(1→3)-glucan, fermentum β-polysaccharide, water-insoluble glucan, callose, laminarin, alkali-soluble β-glucan (PeA3), alkali-soluble polysaccharide (PCAP)
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, lipophosphoglycan, glycoprotein, LPG, glucan, cell wall glucan, polysaccharide, glycoside, β-glucan, β-1, 3-glucan
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Related record ID(s): 43323, 45734, 47152, 47304, 49279, 49282, 50035, 50085, 50648, 50654, 50665, 50671, 50861
NCBI Taxonomy refs (TaxIDs): 357,
33090Reference(s) to other database(s): GTC:G51056AN, GlycomeDB:
157, CCSD:
50049, CBank-STR:4225, CA-RN: 51052-65-4, GenDB:FJ3380871.1
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error