Kijanimicin, the major component of a complex of antibiotics produced by Actinomadura kijaniata nov. sp., has been shown to have the novel tetronic acid structure. Kijanimicin has antitumor activity and is active against P.acnes and is a member of a new class of tetronic acid containing antibiotics of which the tetrocarcins and antlermicins are the only other known members. The latter differ in the structure of the aglycon as well as in the structures of some of the glycosidic components, and full structures for these antiobiotics have not yet been published.

antibiotic, kijanimicin, Actinomadura kijaniata

• Compound ID: 14312
  

  Subst2-(1-4)-b-D-Sugp-(1-17)-+ | a-L-Digp-(1-3)-+ | | | b-L-Digp4Me-(1-4)-a-L-Digp-(1-3)-a-L-Digp-(1-9)-Subst Sug = 3C-methyl-3-nitro-4-amino-2,3,4,6-tetradeoxy-xylo-hexose = SMILES C[C@H]1O{1}[C@@H](O)C[C@](C)(N(=O)=O){4}[C@H]1N; Subst = kijanolide = SMILES C/C3=C/C{17}[C@H](O)/C(C)=C\[C@H]1\C=C(CO)/[C@H](C)C[C@]12OC(=O)/C(=C2/O)C(=O)[C@]5(C)[C@H]3/C=C\[C@@H]4{9}[C@@H](O)[C@@H](C)C[C@H](C)[C@H]45; Subst2 = carbamic acid methyl ester = SMILES CO{1}C(N)=O

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  Structure type: oligomer
  C67H100N2O24
  Trivial name: kijanimicin
  Compound class: glycoside
  Reference(s) to other database(s): GTC:G39749TV
  
   
  
  Actinomadura kijaniata
  CSDB ID 48085 (all data & tools)

Kijanimicin, the major component of a complex of antibiotics produced by Actinomadura kijaniata nov. sp., has been shown to have the novel tetronic acid structure. Kijanimicin has antitumor activity and is active against P.acnes and is a member of a new class of tetronic acid containing antibiotics of which the tetrocarcins and antlermicins are the only other known members. The latter differ in the structure of the aglycon as well as in the structures of some of the glycosidic components, and full structures for these antiobiotics have not yet been published.

antibiotic, kijanimicin, Actinomadura kijaniata

• Compound ID: 14312
  

  Subst2-(1-4)-b-D-Sugp-(1-17)-+ | a-L-Digp-(1-3)-+ | | | b-L-Digp4Me-(1-4)-a-L-Digp-(1-3)-a-L-Digp-(1-9)-Subst Sug = 3C-methyl-3-nitro-4-amino-2,3,4,6-tetradeoxy-xylo-hexose = SMILES C[C@H]1O{1}[C@@H](O)C[C@](C)(N(=O)=O){4}[C@H]1N; Subst = kijanolide = SMILES C/C3=C/C{17}[C@H](O)/C(C)=C\[C@H]1\C=C(CO)/[C@H](C)C[C@]12OC(=O)/C(=C2/O)C(=O)[C@]5(C)[C@H]3/C=C\[C@@H]4{9}[C@@H](O)[C@@H](C)C[C@H](C)[C@H]45; Subst2 = carbamic acid methyl ester = SMILES CO{1}C(N)=O

  Show graphically

  Show legend Show as text

  Structure type: oligomer
  C67H100N2O24
  Trivial name: kijanimicin
  Compound class: glycoside
  Reference(s) to other database(s): GTC:G39749TV
  
   
  
  Actinomadura kijaniata
  CSDB ID 48086 (all data & tools)