Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: leaf
The structure was elucidated in this paperNCBI PubMed ID: 9461665Publication DOI: 10.1021/np970171qJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: Woo ER <wooer
kistmail.kist.re.kr>
Institutions: Division of Applied Science, Korea Institute of Science & Technology, Seoul, South Korea, Department of Biotechnology, Chung-Ang University, An-Sung, Korea
Bioassay-directed chromatographic fractionation of an ethyl acetate extract of the leaves of Acer okamotoanum using HIV-1 integrase afforded a new acylated flavonol glycoside, quercetin 3-0-(2 ",6 "-0-digalloyl)-beta-D-galactopyra (1), together with six known flavonol glycosides and three known phenolic compounds. The structure of the new compound was determined by spectroscopic methods. The most active compounds were quercetin 3-O-(2 "-galloyl)-alpha-L-arabinopyranoside (6) and 1, which exhibited IC50 values of 18.1 +/- 1.3 and 24.2 +/- 6.6 mu g/mL, respectively, against HIV-1 integrase.
iridoid glucosides, secoiridoid glucosides, loganic acid, loganin, Loasa acerifolia, Loasaceae, acerifolioside, tricoloroside methyl ester
Structure type: monomer
Location inside paper: p. 147, column 1, paragraph 3-4, compound 2, compound 3
Compound class: glycoside
Contained glycoepitopes: IEDB_136044,IEDB_136105,IEDB_137472,IEDB_141794,IEDB_190606,IEDB_225177,IEDB_885823,SB_165,SB_166,SB_187,SB_195,SB_7,SB_88
Methods: 13C NMR, 1H NMR, IR, inhibition studies, TLC, ESI-MS, acid hydrolysis, MS, UV, extraction, optical rotation measurement, CC, melting point determination, HMBC, HR-FAB-MS
Biological activity: inhibitory activity against HIV-1 integrase: IC50 = 64.6 μg/mL and 75.2 μg/mL
Related record ID(s): 61854, 61856, 61857, 61858, 61859
NCBI Taxonomy refs (TaxIDs): 47964
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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(later renamed to: Acer pictum ssp. okamotoanum)